Shijiazhuang Zulei commerce Co.,Ltd.
We are professional supplier of bkedbp,maf,bmk,adbf,fubamb,Lidocaine,Sildenafil,Isoniazid,Chloropheniramine maleate,Omeprazole.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
Pregabalin
1.Specification
Production name:Pregabalin 148553-50-8
Cas no.:148553-50-8
Purity: 99% min
MF:C8H17NO2
2. Uses:
Pregabalin, is a new type of GABA receptor agonists, can block the voltage dependence calcium channel to reduce the neurotransmitter release, mainly used for clinical treatment of peripheral neuropathy and auxiliary for the treatment of localized part seizures.
Package:25Kg/drum
3. Function:
1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
2. The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Can also be used to treat pain and anxiety.
4.Specification
Item | Standard | Result |
Appearance | White or almost white crystalline powder | White crystalline powder |
Specific rotation | +9.0~ +11.5° | +10.79° |
PH | 6.0~8.0 | 6.77 |
Loss on drying | ≤0.5% | 0.02% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤0.002% | <0.002% |
Assay (on dried basis) | ≥98.5% | 100.8% |
R-pregabalin(HPLC) | ≤0.5% | 0.33% |
Related substances | S-(+)-mandel ≤0.1% | 0.3% |
Unspecific individual impurity≤0.4% | 0.08% | |
Total impurities≤1.0% | 0.10% | |
Residual solvents | isopropylketone≤3000ppm tetrahydrofuran≤720ppm | 585.0ppm ND |
Conclusion | Comply with the enterprise standard | |
